The guided-mode resonance biosensor: principles, technology, and implementation

Robert Magnusson; Kyu J. Lee; Hafez Hemmati; Yeong Hwan Ko; Brett R. Wenner; Jeffery W. Allen; Monica S. Allen; Susanne Gimlin; Debra Wawro Weidanz

doi:10.1117/12.2288795

20 February 2018 The guided-mode resonance biosensor: principles, technology, and implementation

Robert Magnusson, Kyu J. Lee, Hafez Hemmati, Yeong Hwan Ko, Brett R. Wenner, Jeffery W. Allen, Monica S. Allen, Susanne Gimlin, Debra Wawro Weidanz

Author Affiliations +

Proceedings Volume 10510, Frontiers in Biological Detection: From Nanosensors to Systems X; 105100G (2018) https://doi.org/10.1117/12.2288795
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

The guided-mode resonance (GMR) sensor operates with quasi-guided modes induced in periodic films. The resonance is enabled by 1D or 2D nanopatterns that are expeditiously fabricated. Optical sensors are needed in many fields including medical diagnostics, chemical analyses, and environmental monitoring. Inducing resonance in multiple modes enables extraction of complete bioreaction information including the biolayer thickness, biolayer refractive index, and any change in the refractive index in the background buffer solution. Thus, we refer to this version of the GMR sensor as the complete biosensor. We address the fundamentals, state of technological development, and implementation of this basic sensor modality.

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Robert Magnusson, Kyu J. Lee, Hafez Hemmati, Yeong Hwan Ko, Brett R. Wenner, Jeffery W. Allen, Monica S. Allen, Susanne Gimlin, and Debra Wawro Weidanz "The guided-mode resonance biosensor: principles, technology, and implementation", Proc. SPIE 10510, Frontiers in Biological Detection: From Nanosensors to Systems X, 105100G (20 February 2018); https://doi.org/10.1117/12.2288795

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