Extreme ultraviolet lensless imaging of biological specimen

F. Tuitje; T. Helk; M. Zürch; C. Spielmann

doi:10.1117/12.2507211

4 March 2019 Extreme ultraviolet lensless imaging of biological specimen

F. Tuitje, T. Helk, M. Zürch, C. Spielmann

Proceedings Volume 10890, Label-free Biomedical Imaging and Sensing (LBIS) 2019; 1089029 (2019) https://doi.org/10.1117/12.2507211
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Imaging of biological specimen is one of the most important tools to investigate structures and functionalities in organic components. Improving the resolution of images into the nanometer range call for short wavelengths light sources and large aperture optics. Subsequently, the use of extreme ultraviolet light in the range of 2 nm to 5 nm provides high contrast and high resolution imaging, if it is combined with lensless imaging techniques. We describe important parameters for high resolution lensless imaging of biological samples and specify the required light source properties. To overcome radiation based damage of biological specimen, we discuss the concept of ghost imaging and describe a possible setup towards biological imaging in the extreme ultraviolet range.

Citation Download Citation

F. Tuitje, T. Helk, M. Zürch, and C. Spielmann "Extreme ultraviolet lensless imaging of biological specimen", Proc. SPIE 10890, Label-free Biomedical Imaging and Sensing (LBIS) 2019, 1089029 (4 March 2019); https://doi.org/10.1117/12.2507211

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KEYWORDS

Extreme ultraviolet

Diffraction

Beam splitters

Sensors

Image resolution

Absorption

Cameras

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