The genes that contribute to bipolar disorder and its genetic therapy

Chenjun Su

doi:10.1117/12.2669373

24 March 2023 The genes that contribute to bipolar disorder and its genetic therapy

Chenjun Su

Proceedings Volume 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022); 126112Z (2023) https://doi.org/10.1117/12.2669373
Event: International Conference on Biological Engineering and Medical Science (ICBioMed2022), 2022, Oxford, United Kingdom

Abstract

Bipolar disorder, also called BD, is a kind of severe and frequent mental disease, with considerable morbidity and mortality. It is quite difficult to find out effective way to treat it due to its relatively high complexity compared to other similar diseases. There are different contributors that can lead to BD. Among these, genetic factors dominate. Therefore, it is not useful enough to treat BD with medicine like lithium and lurasidone, which can be used to treat other mental diseases like manic and depression. In genome, there are quite a few genes, including BDNF, 5-HTTLPR, HLA-G and NCAN, etc., associated with bipolar disorder, which provides us with new direction to the treatment. Additionally, genetic therapy seems to show no side effects on patients, providing a better chance in treatment. In this review, it will be discussed that what the genes that lead to BD are and how they contribute to it and the genetic therapy.

Citation Download Citation

Chenjun Su "The genes that contribute to bipolar disorder and its genetic therapy", Proc. SPIE 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112Z (24 March 2023); https://doi.org/10.1117/12.2669373

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