Multiwavelength pulse oximetry in the measurement of hemoglobin fractions

Bernd Manzke; Johannes Schwider; Norbert O. Lutter; Kai Engelhardt; Wilhelm Stork

doi:10.1117/12.238813

24 April 1996 Multiwavelength pulse oximetry in the measurement of hemoglobin fractions

Bernd Manzke, Johannes Schwider, Norbert O. Lutter, Kai Engelhardt, Wilhelm Stork

Proceedings Volume 2676, Biomedical Sensing, Imaging, and Tracking Technologies I; (1996) https://doi.org/10.1117/12.238813
Event: Photonics West '96, 1996, San Jose, CA, United States

Abstract

The two wavelength design of the majority of pulse oximeters assumes only two absorbing hemoglobin fractions, oxyhemoglobin (O₂Hb), and reduced hemoglobin (HHb) irrespective of the presence of methemoglobin (MetHb) and carboxyhemoglobin (COHb). If MetHb or COHb is present, it contributes to the pulse-added absorbance signal and will be interpreted as either HHb or O₂Hb or some combination of the two. In this paper we describe a noninvasive multi-wavelength pulse oximeter measuring O₂Hb, HHb, MetHb, and COHb at a specified accuracy of 1.0%. The system was designed with respect to the results of numerical simulations. It consists of 9 laserdiodes (LDs) and 7 light emitting diodes (LEDs), a 16-bit analog-digital converter (ADC) and has a sampling rate of 16 kHz. The laser didoes and LEDs were coupled into multi-mode fibers and led with a liquid lightguide to the finger clip and then the photodiode. It also presents the results of a clinical study, including a setup with a quartz tungsten halogen lamp (with fiber output) and a diode array spectrometer, a standard pulse oximeter and two in-vitro oximeters (radiometer OSM3 and radiometer ABL 520) as references.

Citation Download Citation

Bernd Manzke, Johannes Schwider, Norbert O. Lutter, Kai Engelhardt, and Wilhelm Stork "Multiwavelength pulse oximetry in the measurement of hemoglobin fractions", Proc. SPIE 2676, Biomedical Sensing, Imaging, and Tracking Technologies I, (24 April 1996); https://doi.org/10.1117/12.238813

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