Influence of red laser irradiation on hemoglobin oxygen saturation and blood volume in human skin in vivo

Alexander A. Stratonnikov; Natalia V. Ermishova; Victor B. Loschenov

doi:10.1117/12.434687

9 July 2001 Influence of red laser irradiation on hemoglobin oxygen saturation and blood volume in human skin in vivo

Alexander A. Stratonnikov, Natalia V. Ermishova, Victor B. Loschenov

Proceedings Volume 4257, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical; (2001) https://doi.org/10.1117/12.434687
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

The aim of the present work was to study the response of hemoglobin oxygen saturation and relative blood volume in human skin in vivo to laser irradiation. The hemoglobin oxygen saturation and relative hemoglobin concentration in skin were evaluated from diffuse reflectance spectra in visible wavelength range. The skin spot at human hand was irradiated with laser beam and hemoglobin oxygen saturation and relative hemoglobin concentration were sampled every two seconds from the center of the irradiated spot. It was evidently observed that hemoglobin oxygen saturation is increased after starting irradiation. During occlusion the oxygen consumption rate was higher in the presence of laser irradiation. However, these effects were observed only at sufficiently high laser fluence rates. The most probable reason is that it is due to thermal effects.

Citation Download Citation

Alexander A. Stratonnikov, Natalia V. Ermishova, and Victor B. Loschenov "Influence of red laser irradiation on hemoglobin oxygen saturation and blood volume in human skin in vivo", Proc. SPIE 4257, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical, (9 July 2001); https://doi.org/10.1117/12.434687

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