Changes of air-tissue ratio evaluated by EBCT after cardiopulmonary resuscitation (CPR): validation in swine

Wolfgang A. Recheis; Antonius H. Schuster; Axel Kleinsasser; Alexander Loeckinger; Christoph Hoermann; Dieter zur Nedden

doi:10.1117/12.428140

21 May 2001 Changes of air-tissue ratio evaluated by EBCT after cardiopulmonary resuscitation (CPR): validation in swine

Wolfgang A. Recheis, Antonius H. Schuster, Axel Kleinsasser, Alexander Loeckinger, Christoph Hoermann, Dieter zur Nedden

Author Affiliations +

Proceedings Volume 4321, Medical Imaging 2001: Physiology and Function from Multidimensional Images; (2001) https://doi.org/10.1117/12.428140
Event: Medical Imaging 2001, 2001, San Diego, CA, United States

Abstract

The purpose was to evaluate changes of the air-tissue ratio (ATR) in previously defined regions of interest after cardiopulmonary resuscitation (CPR) in porcine model. Eight anesthetized and ventilated pigs we scanned in supine position before and 30 minutes after CPR at two different constant PEEP levels (5 cm H₂O, 15 cm H₂O). Volume scans were obtained using 6 mm slices. The gray values of the lung were divided into steps of 100 HU in order to get access to the changes of ATR. ATR was evaluated in ventral, intermediate and dorsal regions of the lung. CPR for 9 minutes led to an uneven distribution of ventilation. In the ventral region, areas with high ATR increased. Areas with normal ATR decreased. In contrast the dorsal regions with low ATR increased. ATR in the intermediate regions remained almost unchanged. Using the higher PEEP level, areas with normal ATR showed a marked increase accompanied by a decrease of areas with low ATR. After CPR, an uneven distribution of lung aeration was detected. According to the impaired hemodynamics, areas with normal ATR decreased and areas with high and low ATR increased. Using higher PEEP levels improved lung aeration.

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Wolfgang A. Recheis, Antonius H. Schuster, Axel Kleinsasser, Alexander Loeckinger, Christoph Hoermann, and Dieter zur Nedden "Changes of air-tissue ratio evaluated by EBCT after cardiopulmonary resuscitation (CPR): validation in swine", Proc. SPIE 4321, Medical Imaging 2001: Physiology and Function from Multidimensional Images, (21 May 2001); https://doi.org/10.1117/12.428140

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