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Laser therapy, using low-energy laser radiation, is being more and more applied. The most applied technology is
transcutaneous radiation of tissues by laser radiation. Originally, a direct action on a pathological site was mostly used,
but recently more attention is given to reflexogenic areas, acupuncture points, and endocrine organ projection sites. The
development of light-conductive engineering made it possible to practically apply intraorgan laser therapy. This
technology is widely spread in gynecology, otorhinolaryngology, urology, gastroenterology, etc. Close to it are different
versions of intratissue laser therapy (intraosteal, periosteal, myofascial). A special kind of laser therapy is laser
hemotherapy. Depending on the techniques and protocol of its application, there are extracorporeal, intravascular, and
supravenous ways of action. According to our comparative investigations, supravenous hemotherapy by its therapeutic
efficacy and major medicinal effects can be well compared with intravascular laser hemotherapy. With good prospects
and efficiency is laser therapy as a combination of laser and other physical factors. Magnetolaser therapy has been
scientifically substantiated and practically applied so far. Theoretically and experimentally substantiated is a combined
application of laser radiation and physical factors such as ultrasound, direct current field, vacuum, cryotherapy,
etc. Experimental research and few so far clinical observations are indicative of prospects of a complex application of
laser radiation and drugs. To improve light absorption, laser radiation is combined with different dyes. Photodynamic
therapy, originally used in oncology, is applied today in treating different diseases. We showed a possibility of using a
number of drugs possessing simultaneously photosensitizing properties to this end. Laser radiation significantly
influences pharmacokinetics and pharmacodynamics of drugs, which gives reason to practically implement laser technologies, based on pharmacomodulating action of laser radiation, to practical medicine.
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