Fluorescence sensing of biological tissue structures using Mn-doped CdS nanoparticles as biomarkers

Volodymyr I. Fediv; Andriy I. Savchuk; Galyna Yu. Rudko; Igor S. Davydenko; Tetyana A. Savchuk; Evgeniy G. Gule; Svitlana A. Ivanchak

doi:10.1117/12.853345

31 December 2009 Fluorescence sensing of biological tissue structures using Mn-doped CdS nanoparticles as biomarkers

Volodymyr I. Fediv, Andriy I. Savchuk, Galyna Yu. Rudko, Igor S. Davydenko, Tetyana A. Savchuk, Evgeniy G. Gule, Svitlana A. Ivanchak

Author Affiliations +

Proceedings Volume 7388, Ninth International Conference on Correlation Optics; 73880Y (2009) https://doi.org/10.1117/12.853345
Event: Correlation Optics 2009, 2009, Chernivsti, Ukraine

Abstract

The present paper describes the growth, absorption and photoluminescence spectra of Mn-doped cadmium sulfide nanoparticles, and application of nanoparticles for cellular imaging. Formation of CTAB-coated CdS:Mn nanoparticles is monitored by optical methods. The optical absorption edge of CdS:Mn nanoparticles is shifted to the higher-energy side as compared to bulk crystals due to the quantum confinement effect. TEM images demonstrate that the average size of CdS:Mn nanoparticles embedded into gelatin matrix is larger than the one of CTAB-coated nanoparticles. The changes of the optical density during the process of the nanoparticles growth are attributed to the increase of their density in the solution. The effects of coverage layer in the PL properties nanosensors are studied by the photoluminescence method. Interactions between CdS:Mn NPs and organic molecules are probed by photoluminescence method, and the results obtained are used for identification of the Kupffer's cells in the histologic specimens of liver.

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Volodymyr I. Fediv, Andriy I. Savchuk, Galyna Yu. Rudko, Igor S. Davydenko, Tetyana A. Savchuk, Evgeniy G. Gule, and Svitlana A. Ivanchak "Fluorescence sensing of biological tissue structures using Mn-doped CdS nanoparticles as biomarkers", Proc. SPIE 7388, Ninth International Conference on Correlation Optics, 73880Y (31 December 2009); https://doi.org/10.1117/12.853345

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