Optimization of a coded aperture coherent scatter spectral imaging system for medical imaging

Joel A. Greenberg; Manu N. Lakshmanan; David J. Brady; Anuj J. Kapadia

doi:10.1117/12.2082110

18 March 2015 Optimization of a coded aperture coherent scatter spectral imaging system for medical imaging

Joel A. Greenberg, Manu N. Lakshmanan, David J. Brady, Anuj J. Kapadia

Proceedings Volume 9412, Medical Imaging 2015: Physics of Medical Imaging; 94125E (2015) https://doi.org/10.1117/12.2082110
Event: SPIE Medical Imaging, 2015, Orlando, Florida, United States

Abstract

Coherent scatter X-ray imaging is a technique that provides spatially-resolved information about the molecular structure of the material under investigation, yielding material-specific contrast that can aid medical diagnosis and inform treatment. In this study, we demonstrate a coherent-scatter imaging approach based on the use of coded apertures (known as coded aperture coherent scatter spectral imaging^{1, 2}) that enables fast, dose-efficient, high-resolution scatter imaging of biologically-relevant materials. Specifically, we discuss how to optimize a coded aperture coherent scatter imaging system for a particular set of objects and materials, describe and characterize our experimental system, and use the system to demonstrate automated material detection in biological tissue.

Citation Download Citation

Joel A. Greenberg, Manu N. Lakshmanan, David J. Brady, and Anuj J. Kapadia "Optimization of a coded aperture coherent scatter spectral imaging system for medical imaging", Proc. SPIE 9412, Medical Imaging 2015: Physics of Medical Imaging, 94125E (18 March 2015); https://doi.org/10.1117/12.2082110

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