Lensless transport-of-intensity phase microscopy and tomography with a color LED matrix

Chao Zuo; Jiasong Sun; Jialin Zhang; Yan Hu; Qian Chen

doi:10.1117/12.2189523

17 July 2015 Lensless transport-of-intensity phase microscopy and tomography with a color LED matrix

Chao Zuo, Jiasong Sun, Jialin Zhang, Yan Hu, Qian Chen

Proceedings Volume 9524, International Conference on Optical and Photonic Engineering (icOPEN 2015); 95241P (2015) https://doi.org/10.1117/12.2189523
Event: International Conference on Optical and Photonic Engineering (icOPEN2015), 2015, Singapore, Singapore

Abstract

We demonstrate lens-less quantitative phase microscopy and diffraction tomography based on a compact on-chip platform, using only a CMOS image sensor and a programmable color LED array. Based on multi-wavelength transport-of- intensity phase retrieval and multi-angle illumination diffraction tomography, this platform offers high quality, depth resolved images with a lateral resolution of ∼3.7μm and an axial resolution of ∼5μm, over wide large imaging FOV of 24mm². The resolution and FOV can be further improved by using a larger image sensors with small pixels straightforwardly. This compact, low-cost, robust, portable platform with a decent imaging performance may offer a cost-effective tool for telemedicine needs, or for reducing health care costs for point-of-care diagnostics in resource-limited environments.

Citation Download Citation

Chao Zuo, Jiasong Sun, Jialin Zhang, Yan Hu, and Qian Chen "Lensless transport-of-intensity phase microscopy and tomography with a color LED matrix", Proc. SPIE 9524, International Conference on Optical and Photonic Engineering (icOPEN 2015), 95241P (17 July 2015); https://doi.org/10.1117/12.2189523

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available