Thermal imaging as a tool for evaluating tumor treatment efficacy

Oshrit A. Hoffer; Merav A. Ben-David; Eyal Katz; Dana Zoltnik Kirshenbaum; Dror Alezra; Yair Zimmer; Itzhak Kelson; Israel Gannot

doi:10.1117/1.JBO.23.5.058001

3 May 2018 Thermal imaging as a tool for evaluating tumor treatment efficacy

Oshrit A. Hoffer, Merav A. Ben-David, Eyal Katz, Dana Zoltnik Kirshenbaum, Dror Alezra, Yair Zimmer, Itzhak Kelson, Israel Gannot

Author Affiliations +

Journal of Biomedical Optics, Vol. 23, Issue 5, 058001 (May 2018). https://doi.org/10.1117/1.JBO.23.5.058001

Abstract

Breast cancer is the most frequently diagnosed cancer among women in the Western world. Thermography is a nonionizing, noninvasive, portable, and low-cost method that can be used in an outpatient clinic. It was tried as a tool to detect breast cancer tumors, however, it had too many false readings. Thermography has been extensively studied as a breast cancer detection tool but was not used as a treatment monitoring tool. The purpose of this study was to investigate the possibility of using thermal imaging as a feedback system to optimize radiation therapy. Patients were imaged with a thermal camera prior and throughout the radiotherapy sessions. At the end of the session, the images were analyzed for temporal vasculature changes through vessels segmentation image processing tools. Tumors that were not responsive to treatment were observed before the radiation therapy sessions were concluded. Assessing the efficacy of radiotherapy during treatment makes it possible to change the treatment regimen, dose, and radiation field during treatment as well as to individualize treatment schedules to optimize treatment effectiveness.

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Oshrit A. Hoffer, Merav A. Ben-David, Eyal Katz, Dana Zoltnik Kirshenbaum, Dror Alezra, Yair Zimmer, Itzhak Kelson, and Israel Gannot "Thermal imaging as a tool for evaluating tumor treatment efficacy," Journal of Biomedical Optics 23(5), 058001 (3 May 2018). https://doi.org/10.1117/1.JBO.23.5.058001

Received: 10 January 2018; Accepted: 28 March 2018; Published: 3 May 2018

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KEYWORDS

Tumors

Thermography

Image filtering

Radiotherapy

Blood vessels

Optical filters

Breast cancer

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