Hyalocytes are resident macrophages residing in the vitreous cortex of the eye. They help maintain optical clarity, manage immunological threats, and respond to vascular insults. Recently, Castanos et al 2020 reported the ability to image these cells using clinical OCT and Hammer et al 2020 demonstrated their appearance using AO OCT. In this study we demonstrate the use of quad detection AO SLO imaging combined with clinical en face OCT in healthy human subjects to observe the dynamic morphological changes and the variable motility of these cells above the retinal surface over extended time intervals.
As techniques of retinal imaging have evolved, anatomic features that were only assessable in the laboratory have become available in the clinic for patient care. The retinal capillaries were initially described on microscope sections in the pathology laboratory. As optical methods have advanced these features have become part of the routine clinical landscape inspected daily by physicians. This paper briefly traces the evolution of these techniques and shows how they fit into the modern diagnostic armamentarium of ophthalmic retinal care.
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