LC-OCT is a recently developed technology for the diagnosis and monitoring of skin pathologies. 3D LC-OCT images with isotropic cellular resolution allow visualization of skin layers and tissue characterization at the cellular level. A dermoscopic imaging system has been coupled to LC-OCT, allowing localization and coverage of lesions, together with characterization of their margins. Finally, segmentations of the epidermal layers and keratinocyte nuclei performed using artificial intelligence allow diagnosis and follow-up of the treatment of skin pathologies in a non-invasive and quantitative way. These tools could help improve the accuracy of clinical diagnosis, allowing early detection of malignant skin tumors.
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