Fluorescence detection is a well-established method for spectroscopy and sensing. However, since dye molecules are dipolar light sources, a large fraction of the emitted photons can be lost. An effective approach to overcome this problem relies on a planar antenna configuration, which beams the radiation pattern of the dye into a narrow cone. A planar antenna works like a Yagi-Uda antenna, but reflector and director elements are made of thin metal films. Here, by introducing a scanning optical fiber, which incorporates the reflector or the director, we demonstrate a tunable planar antenna for spectroscopic and sensing applications. Our results show that the radiation pattern narrows down to 26 degrees (FWHM), which implies a high collection efficiency by low-NA optics.
Electrical Impedance Tomography (EIT) is a method used to record the impedance distribution within a target. The best-known application of EIT is lung diagnostics using imaging algorithms. However, apart from this, there are individual research projects dealing with imaging analysis at the cellular level. For example, cell analysis using EIT can help to distinguish diseased cells from healthy cells. To achieve this goal, an existing EIT system was combined with a new EIT chip in a first step. This chip allows analysis in very small dimensions. Various parameters such as the diameter of the measuring environment, the necessary conductive solutions or the measuring methods used were varied and evaluated. In a next step, various image reconstructions were carried out using data acquired with C. elegans.
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