Ms. Inna H. Gertsenshteyn Profile

Inna H. Gertsenshteyn

PhD Student

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 16 March 2020 Presentation + Paper

Dependence of radiomics features on CT image acquisition and reconstruction parameters using a cadaveric liver

Joseph Foy, Inna Gertsenshteyn, Hania Al-Hallaq, Samuel Armato, William Sensakovic

Proceedings Volume 11314, 113140U (2020) https://doi.org/10.1117/12.2551155

KEYWORDS: Image acquisition, Liver, Computed tomography, Feature extraction, CT reconstruction, Fractal analysis, Magnetic resonance imaging, Tissues, Manufacturing, Radiology

Read Abstract +

Studies investigating variations in radiomic features due to changes in image acquisition and reconstruction parameters have focused on non-human phantoms to limit the exposure to human subjects. This study investigated such variations in the computed tomography (CT) scans of a cadaveric human liver. A reference CT scan of a normal cadaveric liver and 16 modified scans were acquired with one parameter changed from the reference for each modified scan: two iterative reconstruction strength levels, one reconstruction kernel, one slice thickness, one coronal view, one sagittal view, one field of view (FOV), two pitch levels, one slice interval, two CTDIvol levels, three kV settings, and one scan acquired using a scanner from another manufacturer. The liver was segmented in each scan, and 142 radiomic features were calculated on each slice across all scans. Unpaired Student’s t-tests assessed significant differences in feature distributions between reference and modified scans for all features after correcting for multiple comparisons (p<0.0004). Assessments were repeated after normalizing pixel value histograms for each scan. Variations in tube voltage, pitch, and slice interval resulted in the smallest number of features reflecting significant differences. Variations in FOV and scan orientation resulted in the largest number of features reflecting significant differences. Fractal features were relatively robust to differences among parameters, while first-order features were sensitive to these differences by comparison. After normalization, first-order features improved agreement between modified and reference scans, while higher-order features were not greatly affected.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years