We investigated starvation-induced changes in the relative nanoviscosity of a cancer cell. Fluorescence correlation spectroscopy was used to determine the movement of GFP particles in the cell cytoplasm and calculate diffusion coefficients during starvation for 96 hrs. Water efflux from cells caused changes in cell volume throughout starvation. A few folds increase in this physical quantity was observed during cell death. Morphological changes during starvation were recorded using confocal microscopy.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.