KEYWORDS: Transducers, Whole body imaging, In vivo imaging, 3D image processing, Ultrasonography, Visualization, Photoacoustic imaging, Information visualization, Imaging systems, Tissues
In photoacoustic images with mechanical scanning of single-element ultrasound transducers, respiratory movements generate distortion in data due to slow imaging speed. To overcome this technical issue, we propose an ultrasound-guided breath-compensation method for volumetric photoacoustic data. We have successfully corrected the breath-related distortion by using simultaneously acquired ultrasound data. The resulting three-dimensional photoacoustic images can visualize volumetric hemoglobin oxygen saturation map in the whole body of mice. We believe that these results can provide a more accurate analytical perspective for biomedical imaging studies.
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