Bladder cancer is widely spread. Moreover, carcinoma in situ can be difficult to diagnose as it may be difficult to see,
and become invasive in 50 % of case. Non invasive diagnosis methods like photodynamic or autofluorescence
endoscopy allow enhancing sensitivity and specificity. Besides, bladder tumors can be multifocal. Multifocality
increases the probability of recurrence and infiltration into bladder muscle. Analysis of spatial distribution of tumors
could be used to improve diagnosis. We explore the feasibility to combine fluorescence and spatial information on
phantoms. We developed a system allowing the acquisition of consecutive images under white light or UV excitation
alternatively and automatically along the video sequence. We also developed an automatic image processing algorithm
to build a partial panoramic image from a cystoscopic sequence of images. Fluorescence information is extracted from
wavelength bandpass filtered images and superimposed over the cartography. Then, spatial distribution measures of
fluorescent spots can be computed. This cartography can be positioned on a 3D generic shape of bladder by selecting
some reference points. Our first results on phantoms show that it is possible to obtain cartography with fluorescent spots
and extract quantitative information of their spatial distribution on a "wide" field of view basis.
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