Dr. Xin Chen Profile

Dr. Xin Chen

at BioPharmX Inc

SPIE Involvement:

Author

Publications (5)

Proceedings Article | 5 March 2019 Paper

Multimodal microscopy toolkit for visualizing multicomponent topical drug formulations in humans

Alexander Fast, Sinyoung Jeong, Maiko Hermsmeier, Akira Yamamoto, Xin Chen, Kin Chan, Conor Evans

Proceedings Volume 10882, 108822J (2019) https://doi.org/10.1117/12.2510157

KEYWORDS: Tissues, Fluorescence lifetime imaging, Visualization, Skin, Raman spectroscopy, Microscopy, Confocal microscopy, Absorption, Multiphoton tomography, Natural surfaces

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Proceedings Article | 14 March 2018 Presentation

Effects of endogenous fluorescence from ex vivo human facial skin specimens in the pharmacokinetic study of a topical minocycline gel using two-photon excitation fluorescence (2PEF) and fluorescence lifetime imaging microscopy (FLIM) (Conference Presentation)

Maiko Hermsmeier, Sinyoung Jeong, Akira Yamamoto, Xin Chen, Usha Nagavarapu, Conor Evans, Kin Chan

Proceedings Volume 10475, 104750H (2018) https://doi.org/10.1117/12.2294403

KEYWORDS: Skin, Luminescence, Fluorescence lifetime imaging, Microscopy, Integrating spheres, Tissues, Microscopes, Safety, Drug development, Objectives

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Proceedings Article | 14 March 2018 Presentation

Fluorescence lifetime imaging microscopy (FLIM) for visualization of targeted drug delivery and local distribution in skin of a single daily dose of topical minocycline gel: an update on translational research from preclinical to clinical (Conference Presentation)

Sinyoung Jeong, Maiko Hermsmeier, Sam Osseiran, Akira Yamamoto, Xin Chen, Usha Nagavarapu, Conor Evans, Kin F. Chan, AnnaMarie Daniels

Proceedings Volume 10467, 104670J (2018) https://doi.org/10.1117/12.2294084

KEYWORDS: Fluorescence lifetime imaging, Microscopy, Luminescence, Skin, Visualization, Translational research, Pharmacology, Toxicology, Nonlinear optics

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Proceedings Article | 19 April 2017 Presentation

Visualization of drug distribution of topical minocycline in human facial skin with fluorescence microscopy (Conference Presentation)

Maiko Hermsmeier, Tanvee Sawant, Diana Lac, Akira Yamamoto, Xin Chen, Usha Nagavarapu, Conor Evans, Kin Foong Chan

Proceedings Volume 10046, 100460A (2017) https://doi.org/10.1117/12.2256621

KEYWORDS: Luminescence, Visualization, Microscopy, Skin, Tissues, Bacteria, Inflammation, Photomedicine, Current controlled current source

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Proceedings Article | 19 April 2017 Presentation

Optical microscopy of targeted drug delivery and local distribution in skin of a topical minocycline: implications in translational research and guidance for therapeutic dose selection (Conference Presentation)

Maiko Hermsmeier, Tanvee Sawant, Diana Lac, Akira Yamamoto, Xin Chen, Susan Huang, Usha Nagavarapu, Conor Evans, Kin Foong Chan, AnnaMarie Daniels

Proceedings Volume 10037, 100370K (2017) https://doi.org/10.1117/12.2256790

KEYWORDS: Skin, Luminescence, Microscopy, Safety, Optical microscopy, Translational research, In vitro testing, Molecules, Toxicity, Vehicle control

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