Dr. Zhigang Zhao Profile

Dr. Zhigang Zhao

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Proceedings Article | 15 November 2018 Paper

X-ray phase-contrast imaging using cascade Talbot-Lau interferometers

Ji Li, Jianheng Huang, Yaohu Lei, Xin Liu, Zhigang Zhao

Proceedings Volume 10964, 1096469 (2018) https://doi.org/10.1117/12.2506502

KEYWORDS: X-rays, Interferometers, X-ray imaging, Imaging systems, X-ray sources, Phase interferometry, X-ray technology, Tissues

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Grating-based X-ray phase-contrast imaging (XPCI), have shown great potential for biological and medical imaging applications. However, the fabrication of the absorption grating, an indispensable element in conventional Talbot-Lau interferometer (TLI), making it a great challenge to this technology into practical use. In this paper, we implemented a cascade TLI (CTLI) for XPCI composed by a TLI and an inverse TLI, the self-image of TLI being used as the source of the inverse TLI, with the purpose to avoid the fabrication of small-period high aspect-ratio absorption gratings. Experiments validated the method and demonstrated the versatility and tunability of the system. The angular sensitivity as a function of the sample position was measured and discussed. Results show that the highest sensitivity is obtained, when the investigated object is close to any of two phase gratings. Furthermore, a CTLI with interference fringes being magnified to be directly detected by a common large-area detector would be established using this method. This will be useful for designing an XPCI system for applications of biomedical imaging in large field of view.

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