Dr. Zhixiong Hu Profile

Dr. Zhixiong Hu

at National Institute of Metrology

SPIE Involvement:

Author

Publications (23)

Proceedings Article | 29 December 2023 Paper

Liquid-based scattering microspheres phantom for resolution evaluation of optical coherence tomography

Lei Yang, Liangcheng Duan, Xiang Ma, Xiaowei Zhao, Fei Li, Baoyu Hong, Wenli Liu, Zhixiong Hu

Proceedings Volume 12975, 129750O (2023) https://doi.org/10.1117/12.3015627

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Proceedings Article | 18 December 2023 Paper

Investigation of the ophthalmic optical coherence tomography lateral resolution measurement using the standard test method

Xiaowei Zhao, Wenli Liu, Zhixiong Hu, Liangcheng Duan, Qingqing Wang, Xing Wei, Fei Li, Baoyu Hong

Proceedings Volume 12963, 129631T (2023) https://doi.org/10.1117/12.3000080

KEYWORDS: Optical coherence tomography, Standards development, Image resolution, Image quality standards, Point spread functions, Eye

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Proceedings Article | 27 November 2023 Poster + Paper

Exploration of the transfer standard device for rebound tonometer

Ruidan Xue, Wenli Liu, Baoyu Hong, Yuanhang Cao, Zhixiong Hu

Proceedings Volume 12770, 127702O (2023) https://doi.org/10.1117/12.2687437

KEYWORDS: Eye, Polydimethylsiloxane, Elasticity, Standards development, Cornea, Film thickness, Water, Metals, Deformation, Materials properties

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Proceedings Article | 19 December 2022 Poster + Paper

Metrology and calibration system of ophthalmic optical standard models based on time-domain OCT system

Wenli Liu, Junbang Zhao, Liangcheng Duan, Zhixiong Hu

Proceedings Volume 12319, 123191R (2022) https://doi.org/10.1117/12.2644125

KEYWORDS: Standards development, Calibration, Metrology, Refractive index, Optical coherence tomography, Image filtering, Eye models, Eye, Data modeling, Imaging systems

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Proceedings Article | 19 December 2022 Poster + Paper

Development of geometric parameters metrology system for contact lens based on spectral-domain OCT

Liangcheng Duan, Wenli Liu, Zhixiong Hu, Xiang Ma, Fei Li, Baoyu Hong, Junbang Zhao

Proceedings Volume 12320, 1232021 (2022) https://doi.org/10.1117/12.2643956

KEYWORDS: Optical coherence tomography, Calibration, Metrology, Technology, Imaging systems, Contact lenses, Image processing, Signal to noise ratio, Signal processing, LabVIEW

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Proceedings Article | 19 December 2022 Poster + Paper

Comparison of measurement results of multiple transfer standards in different non-contact tonometers

Ruidan Xue, Wenli Liu, Baoyu Hong, Zhixiong Hu

Proceedings Volume 12320, 1232023 (2022) https://doi.org/10.1117/12.2644086

KEYWORDS: Eye, Standards development, Eye models, Manufacturing, Cornea, Calibration, Metrology, Instrument modeling, Time metrology, Switching

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Proceedings Article | 24 November 2021 Paper

Intra-cavity absorption gas sensing network based on hybrid DWDM and TDM

Liangcheng Duan, Wenli Liu, Zhixiong Hu, Guangyao Wang, Haiwei Zhang, Ying Lu

Proceedings Volume 12065, 120653S (2021) https://doi.org/10.1117/12.2607121

KEYWORDS: Dense wavelength division multiplexing, Absorption, Time division multiplexing, Sensing systems, Active remote sensing, Optical filters, Networks, Optical switching, Multiplexing, Photonic crystal fibers

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Proceedings Article | 31 August 2021 Paper

Development of metrology and calibration device for ophthalmic optical instruments: fundus cameras

Liangcheng Duan, Xiuyu Li, Wenli Liu, Zhixiong Hu, Baoyu Hong

Proceedings Volume 11907, 119072Y (2021) https://doi.org/10.1117/12.2603191

KEYWORDS: Eye, Eye models, Cameras, Metrology, Calibration, Retina, Optical components, Cornea, 3D modeling, Vitreous

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Proceedings Article | 28 February 2021 Paper

Development of key parameters metrology and calibration equipment for medical laser therapy apparatus

Liangcheng Duan, Wenli Liu, Zhixiong Hu, Baozhong Xu, Fubao Wu, Jiayi Yang, Kai Zhong, Jianquan Yao

Proceedings Volume 11781, 117810R (2021) https://doi.org/10.1117/12.2591724

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Proceedings Article | 5 November 2020 Paper

A large imaging-depth SSOCT system with one reference arm

Hongting Wang, Wenli Liu, Zhixiong Hu, Xuesong Fu, Xiuyu Li, Liangcheng Duan

Proceedings Volume 11567, 1156744 (2020) https://doi.org/10.1117/12.2580292

KEYWORDS: Optical coherence tomography, Imaging systems

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Proceedings Article | 5 November 2020 Paper

Measurement error of spatial frequency response based on sinusoidal Siemens Star

Runjia Yang, Fei Li, Baoyu Hong, Zhixiong Hu

Proceedings Volume 11567, 115673V (2020) https://doi.org/10.1117/12.2580250

KEYWORDS: Stars, Spatial frequencies, Modulation, Metrology, Image processing, Detection and tracking algorithms, Calibration, Target recognition, Phase shifts

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Proceedings Article | 31 January 2020 Paper

Two-step phase-shifting sectioning structured illumination microscopy

Hongting Wang, Zhixiong Hu, Wenli Liu, Fei Li, Xiuyu Li

Proceedings Volume 11427, 1142713 (2020) https://doi.org/10.1117/12.2551040

KEYWORDS: Phase shifts, Microscopy, Image retrieval, 3D metrology

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Proceedings Article | 18 December 2019 Paper

One-shot optical sectioning structured illumination microscopy

Hongting Wang, Wenli Liu, Zhixiong Hu, Xiuyu Li, Baoyu Hong

Proceedings Volume 11338, 113380F (2019) https://doi.org/10.1117/12.2541477

KEYWORDS: Microscopy, Phase shifts, Fringe analysis, Fourier transforms, Microscopes

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Proceedings Article | 17 May 2019 Paper

Point spread function measurement and analysis of three dimensional optical imaging system

Xiuyu Li, Tao Wen, Zhixiong Hu, Hongting Wang, Wenli Liu, Baoyu Hong, Chenyang Zhong

Proceedings Volume 11170, 111701C (2019) https://doi.org/10.1117/12.2533034

KEYWORDS: Point spread functions, Imaging systems, Optical coherence tomography, 3D image processing, Image resolution, Confocal laser scanning microscopy, Confocal microscopy, 3D metrology, Surface finishing, Particles

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Proceedings Article | 18 January 2019 Paper

The studies of noninvasive blood glucose monitoring using optical coherence tomography

Ran Li, Guozhong Liu, Zhixiong Hu, Xiaopeng Xia, Tao Liu

Proceedings Volume 10839, 108390V (2019) https://doi.org/10.1117/12.2505124

KEYWORDS: Glucose, Blood, Scattering, Optical coherence tomography, Skin, Light scattering, Tissue optics, Tissues, Natural surfaces, Calibration

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Proceedings Article | 19 October 2016 Paper

A standard model eye with micro scale multilayer structure for ophthalmic optical coherence tomography equipment

Zhenggang Cao, Zengqian Ding, Zhixiong Hu, Tao Wen, Wen Qiao, Wenli Liu

Proceedings Volume 10155, 101552E (2016) https://doi.org/10.1117/12.2247009

KEYWORDS: Optical coherence tomography, Eye models, Instrument modeling, Eye, Ophthalmology, Metrology

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Optical coherence tomography (OCT) has been widely applied in diagnosis of eye diseases during the last 20 years. Differing from traditional two-dimension imaging technologies, OCT could also provide cross-sectional information of target tissues simultaneously and precisely. As well known, axial resolution is one of the most critical parameters impacting the OCT image quality, which determines whether an accurate diagnosis could be obtained. Therefore, it is important to evaluate the axial resolution of an OCT equipment. Phantoms always play an important role in the standardization and validation process. Here, a standard model eye with micro-scale multilayer structure was custom designed and manufactured. Mimicking a real human eye, analyzing the physical characteristic of layer structures of retina and cornea in-depth, appropriate materials were selected by testing the scattering coefficient of PDMS phantoms with difference concentration of TiO₂ or BaSO₄ particles. An artificial retina and cornea with multilayer-films which have a thickness of 10 to 60 micrometers for each layer were fabricated using spin coating technology. Considering key parameters of the standard model eye need to be traceable as well as accurate, the optical refractive index and layer structure thicknesses of phantoms were verified by utilizing Thickness Monitoring System. Consequently, a standard OCT model eye was obtained after the retinal or corneal phantom was embedded into a water-filled model eye which has been fabricated by 3D printing technology to simulate ocular dispersion and emmetropic refraction. The eye model was manufactured with a transparent resin to simulate realistic ophthalmic testing environment, and most key optical elements including cornea, lens and vitreous body were realized. By investigating with a research and a clinical OCT system respectively, the OCT model eye was demonstrated with similar physical properties as natural eye, and the multilayer film measurement provided an effective method to rapidly evaluate the axial resolution of ophthalmic OCT devices.

Proceedings Article | 27 September 2016 Paper

A standard test method based on point spread function for three-dimensional imaging system

Tao Wen, Jinxin Dong, Zhixiong Hu, Zhenggang Cao, Wenli Liu, Jianlin Wang

Proceedings Volume 9684, 96842F (2016) https://doi.org/10.1117/12.2243260

KEYWORDS: Point spread functions, 3D image processing, Imaging systems, Image resolution, Optical coherence tomography, Surface finishing, Particles, Scattering, Silicon, 3D metrology

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Proceedings Article | 7 August 2015 Paper

A miniaturized and integrated system to measure key parameters of ophthamic optical coherence tomography equipment

Xiaoyu Fu, Zhixiong Hu, Chunfeng Ge, Bingtao Hao, Wenli Liu, Baoyu Hong, Dongfang Jia

Proceedings Volume 9623, 96230H (2015) https://doi.org/10.1117/12.2193550

KEYWORDS: Optical coherence tomography, Image resolution, Imaging systems, System integration, Light, Spectral resolution, Charge-coupled devices, LabVIEW, Data acquisition, Data processing

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Proceedings Article | 3 December 2014 Paper

Test target for characterizing 3D resolution of optical coherence tomography

Zhixiong Hu, Bingtao Hao, Wenli Liu, Baoyu Hong, Jiao Li

Proceedings Volume 9297, 92971S (2014) https://doi.org/10.1117/12.2073062

KEYWORDS: Optical coherence tomography, 3D acquisition, 3D metrology, Image resolution, 3D printing, Optical resolution, Optical fabrication, Profilometers, 3D image processing, Image quality

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Proceedings Article | 18 November 2014 Paper

Optical coherence tomography imaging of microfluidic pattern with different refractive index contrast

Zhixiong Hu, Bingtao Hao, Wenli Liu, Baoyu Hong

Proceedings Volume 9268, 926816 (2014) https://doi.org/10.1117/12.2070982

KEYWORDS: Optical coherence tomography, Microfluidics, Refractive index, Lab on a chip, Coherence imaging, Microfluidic imaging, Glasses, Confocal microscopy, 3D image processing, Microscopes

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Proceedings Article | 18 September 2014 Paper

Metrology research on PDMS phantoms for evaluating resolution performance of OCT systems

Bingtao Hao, Wenli Liu, Zhixiong Hu, Baoyu Hong, Jiao Li

Proceedings Volume 9282, 92820H (2014) https://doi.org/10.1117/12.2068500

KEYWORDS: Point spread functions, Optical coherence tomography, Silicon, Particles, Metrology, Solids, Surface finishing, Image resolution, Polymers, Ultrasonics

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Proceedings Article | 17 September 2014 Paper

A physical model eye with 3D resolution test targets for optical coherence tomography

Zhixiong Hu, Wenli Liu, Baoyu Hong, Bingtao Hao, Lele Wang, Jiao Li

Proceedings Volume 9230, 92301H (2014) https://doi.org/10.1117/12.2067974

KEYWORDS: Optical coherence tomography, 3D modeling, Eye models, Eye, 3D acquisition, 3D image processing, Tissue optics, Biomedical optics, Systems modeling, 3D printing

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Proceedings Article | 23 August 2013 Paper

Integrated microfluidic spectroscopic sensor using arrayed waveguide grating

Zhixiong Hu, Andrew Glidle, Charles Ironside, Marc Sorel, Michael Strain, Jonathan Cooper, Huabing Yin

Proceedings Volume 8911, 89110A (2013) https://doi.org/10.1117/12.2033213

KEYWORDS: Waveguides, Microfluidics, Sensors, Electron beam lithography, Spectroscopes, Luminescence, Optical lithography, Silica, Reactive ion etching, Charge-coupled devices

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Showing 5 of 23 publications

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