Towards high-sensitivity and low-dose medical imaging with laser x-ray sources

D. Stutman; N. Safca; P. Tomassini; E. Anghel; C. A. Ur

doi:10.1117/12.2664833

8 June 2023 Towards high-sensitivity and low-dose medical imaging with laser x-ray sources

D. Stutman, N. Safca, P. Tomassini, E. Anghel, C. A. Ur

Proceedings Volume 12582, Compact Radiation Sources from EUV to Gamma-rays: Development and Applications; 1258207 (2023) https://doi.org/10.1117/12.2664833
Event: SPIE Optics + Optoelectronics, 2023, Prague, Czech Republic

Abstract

Phase contrast X-ray imaging can be much more sensitive to soft tissue lesions than conventional absorption contrast X-ray imaging, being a potential game changer for medical imaging. A phase contrast method well suited for clinical implementation is the grating interferometry. We show that by using μm period multi-meter long interferometers one can strongly increase the phase sensitivity and lower the dose towards soft tissue imaging applications such mammography. Conventional X-ray tubes do not provide, however, sufficient X-ray flux for clinical imaging with such long interferometers. Instead, 100-TW class lasers could produce highly directional and intense X-ray sources ideal for high sensitivity medical interferometry. We present the X-ray source characteristics required for clinical interferometry, advantages and disadvantages of betatron versus inverse Compton scattering sources for clinical application, and some practical considerations towards laser based interferometric medical imaging.

Conference Presentation

Citation Download Citation

D. Stutman, N. Safca, P. Tomassini, E. Anghel, and C. A. Ur "Towards high-sensitivity and low-dose medical imaging with laser x-ray sources", Proc. SPIE 12582, Compact Radiation Sources from EUV to Gamma-rays: Development and Applications, 1258207 (8 June 2023); https://doi.org/10.1117/12.2664833

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