Recently we developed the open-source FlexNIRS: a battery-operated, wireless, wearable oximeter whose self-calibrating geometry allows measurements of oxygen saturation in tissue. The first implementation of the device operating at 100 Hz has been validated and is enrolled in several measurement campaigns across different research laboratories. A recent firmware upgrade provides 266 Hz sampling rate, and hardware modifications provide improved form factor, wearability, and multi-modal acquisition. The new version is currently adopted in multiple clinical measurement campaigns focusing on pulsatile component analysis. We will present the instrument performance, its recent and future upgrades, and the applications where the device is currently in use.
Infants born at an extremely low gestational age are at an increased risk of intraventricular hemorrhaging during the first three postnatal days. We have built a standalone easy-to-use multi-wavelength multi-distance diffuse correlation spectroscopy system, which utilizes three time-multiplexed long coherence lasers at 785, 808, and 853 nm, single photon detectors, and photon time-tagging electronics to simultaneously quantify cerebral blood flow, tissue optical properties, and blood oxygen saturation. The system has been designed specifically for use on preterm infants. The device shows good agreement with a commercially available NIRS-DCS system. We are currently monitoring preterm infants and will show results.
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