Prof. Sylvain Marchand-Adam Profile

Prof. Sylvain Marchand-Adam

at Univ de Tours

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 15 February 2021 Presentation + Paper

Traction bronchiectasis identification and quantitative biomarkers for follow-up in nonspecific interstitial pneumonia

Marjorie Latrasse, Simon Rennotte, Pierre-Yves Brillet, Sylvain Marchand-Adam, Catalin Fetita

Proceedings Volume 11597, 115970T (2021) https://doi.org/10.1117/12.2580657

KEYWORDS: Lung, Pulmonary function tests, Inflammation, Databases, Convolutional neural networks

Read Abstract +

As a subclass of interstitial lung diseases, nonspecific interstitial pneumonia (NSIP), defined by an association of inflammation and fibrotic lung lesions, leads to progressive loss of pulmonary function and premature mortality. Among fibrosis manifestations, traction bronchiectasis (TB) is one of the most critical, its presence being associated to poor prognosis. Accurate follow up is crucial to treatment decision and adaptation. In this paper we propose quantitative biomarkers for TB, associating spatial localization and severity measures. Bronchial tree segmentation and TB identification first exploited a semi-automatic approach for the definition of the ground truth, then used an automatic method involving a convolutional neural network. The CNN training/testing database included 73/18 patients respectively, with both baseline and follow up exams at one year; the detection performance was assessed in terms of precision, recall and F1-score. For both ground truth and CNN-segmented data, the following TB biomarkers were derived: TB ratio over total airway, airway volume, normalized tree length, and airway caliber (absolute and relative) deviation from the normal 2-power decrease law. A correlation study between the TB biomarkers and the initial and follow up pulmonary function tests was conducted. Among ground truth-based TB biomarkers, airway volume, normalized tree length, absolute caliber deviation and TB ratio over total airway showed significant negative correlation with both initial and follow-up pulmonary function parameters, manifesting as potential prognosis biomarkers. Among CNN-based TB biomarkers, airway volume, normalized tree length, relative and absolute caliber deviation showed significant negative correlation with follow-up pulmonary function parameters confirming their predictive potential.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years