Hybrid interfaces for a new class of optical biosensors

L. De Stefano; A. Caliò; J. Politi; P. Giardina; I. Redina; I. Rea

doi:10.1117/12.2017615

3 May 2013 Hybrid interfaces for a new class of optical biosensors

L. De Stefano, A. Caliò, J. Politi, P. Giardina, I. Redina, I. Rea

Proceedings Volume 8774, Optical Sensors 2013; 87741G (2013) https://doi.org/10.1117/12.2017615
Event: SPIE Optics + Optoelectronics, 2013, Prague, Czech Republic

Abstract

Interfaces play a key role in optical biosensor fabrication: biological molecules need to be integrated with inorganic transducers, both electrical and optical, preserving their functions and specificity. Single DNA stands, proteins, enzymes, and antibodies must be blocked on surface by absorption or covalently, depending on different chemistry used. In case of proteins and antibodies, also orientation of biological molecules is very important. In this work, we present our results on a biological passivation procedure that employs hydophobins, small amphiphilic proteins. Since these proteins complex with sugars in nature, we also suggest their utilization as functional layer in optical biosensor for glucose.

Citation Download Citation

L. De Stefano, A. Caliò, J. Politi, P. Giardina, I. Redina, and I. Rea "Hybrid interfaces for a new class of optical biosensors", Proc. SPIE 8774, Optical Sensors 2013, 87741G (3 May 2013); https://doi.org/10.1117/12.2017615

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