Volume Table of Contents

PROCEEDINGS VOLUME 12611

INTERNATIONAL CONFERENCE ON BIOLOGICAL ENGINEERING AND MEDICAL SCIENCE (ICBIOMED2022) | 7-13 NOVEMBER 2022

Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022)

Editor(s): Gary Royle, Steven M. Lipkin

Editor Affiliations +

IN THIS VOLUME

6 Sessions, 239 Papers, 0 Presentations

Front Matter: Volume 12611 (1)

Biology and Ecology (17)

Biomedical Engineering (34)

Medical Science (154)

Pharmaceutical Science (32)

Erratum: Volume 12611 (1)

INTERNATIONAL CONFERENCE ON BIOLOGICAL ENGINEERING AND MEDICAL SCIENCE (ICBIOMED2022)

7-13 November 2022

Oxford, United Kingdom

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Front Matter: Volume 12611

Front Matter: Volume 12611 Open Access

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261101 (2023) https://doi.org/10.1117/12.2678294

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Biology and Ecology

The regulation of the receptor of aspartame Paper

Liyuan Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261102 (2023) https://doi.org/10.1117/12.2668898

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The effect of human activities on marine biodiversity Paper

Bolun Pan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261103 (2023) https://doi.org/10.1117/12.2669385

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Fermented plant-based cereal beverages as a good alternative to fermented milk beverages: from nutritional composition, microorganisms, and sensory properties Paper

Bingqi Liang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261104 (2023) https://doi.org/10.1117/12.2669960

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Research progress on soil microbial diversity technology Paper

Boyu Ma

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261105 (2023) https://doi.org/10.1117/12.2669544

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Intrinsically disordered proteins in anhydrobiosis challenge the cognition of traditional proteins Paper

Pengcheng Xiong

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261106 (2023) https://doi.org/10.1117/12.2669624

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Advances in plant immunity and disease resistance breeding Paper

Tongyu Zhao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261107 (2023) https://doi.org/10.1117/12.2669038

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Impacts of climate change on human health in the U.S. Paper

Jiajin Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261108 (2023) https://doi.org/10.1117/12.2669538

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Ginkgo biloba L.: decline of the Ginkgoaceae and future protection of the only species remained Paper

Xinran Gao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261109 (2023) https://doi.org/10.1117/12.2669540

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Investigation of suppressing Anopheles stephensi reproduction with RNAi Paper

Breeze Mancheng Hong

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110A (2023) https://doi.org/10.1117/12.2669367

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A review on the application of mitochondrial DNA sequences to population genetic study of lepidopteran insects in China Paper

Haoyu Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110B (2023) https://doi.org/10.1117/12.2668996

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Global warming and its effects on cetaceans Paper

Zhifan Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110C (2023) https://doi.org/10.1117/12.2669626

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Effects of climate change on the abiotic interactions and adaptions of plants Paper

Xin Hai

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110D (2023) https://doi.org/10.1117/12.2669690

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Effects of global warming on plant phenology Paper

Ziti Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110E (2023) https://doi.org/10.1117/12.2669345

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Effects of sweeteners and fruit additions on yogurt quality Paper

Yipeng Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110F (2023) https://doi.org/10.1117/12.2669046

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Impacts of climate change on snakes in mangrove forests Paper

Xinyu Jiang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110G (2023) https://doi.org/10.1117/12.2669871

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The effect of climate change on the lifestyle of polar bears Paper

Che Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110H (2023) https://doi.org/10.1117/12.2669354

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Effects of arbuscular mycorrhizal and ectomycorrhizal on plant stress resistance Paper

Xinni Yao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110I (2023) https://doi.org/10.1117/12.2669029

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Biomedical Engineering

Pre-clinical Alzheimer's disease diagnosis using non-invasive neuroimaging tools Paper

Jinren Yu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110J (2023) https://doi.org/10.1117/12.2669353

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Prospects and ethical issues of artificial intelligence in medicine Paper

Qianyu Liang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110K (2023) https://doi.org/10.1117/12.2669474

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Research on the design of rehabilitation robot system based on neural signal control Paper

Fanqi Guo

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110L (2023) https://doi.org/10.1117/12.2669553

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The application of deep learning for COVID-19 diagnosis and treatment Paper

Jiahua Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110M (2023) https://doi.org/10.1117/12.2669642

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An analysis of the mechanism and prospect of AlphaFold2 model based on machine learning and neural network Paper

Chengrui Liang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110N (2023) https://doi.org/10.1117/12.2669676

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AlphaFold2 protein structure prediction based on computer vision Paper

Zihan Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110O (2023) https://doi.org/10.1117/12.2669377

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A new approach to protein sequence visualization based on PCA with Fourier low-pass filter Paper

Yi Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110P (2023) https://doi.org/10.1117/12.2669482

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Review on the modularization of prosthetic limbs Paper

Kechen Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110Q (2023) https://doi.org/10.1117/12.2669356

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Cross-modal image segmentation and synthesis in medical imaging Paper

Xiaolong Wu, Zhimin Gan, Jiaxi Xie, Haiyi Lou, Zhengxing Yan, Qiqi Jia, Yingchun Yuan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110R (2023) https://doi.org/10.1117/12.2669536

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Natural language processing: mining adverse drug reactions from medical texts Paper

Junjie Lai, Sophia Zhu, Chuang Wang, Bohan Yin, Yihang Zhou, Haotong Hu, Chunya Ji

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110S (2023) https://doi.org/10.1117/12.2669576

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Exploring the mechanism of action of three agents white powder in the care for pulmonary diseases based on network pharmacology and technology for molecular docking Paper

Aiqi Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110T (2023) https://doi.org/10.1117/12.2669537

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Implementation of detection of skin lesions in monkeypox based on a deep learning model: using an improved bilinear pooling model Paper

Wenshu Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110U (2023) https://doi.org/10.1117/12.2669408

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Application of microchips for various targets detection Paper

Yixuan Xu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110V (2023) https://doi.org/10.1117/12.2669064

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Application of different biosensors for biomarkers analysis Paper

Ang Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110W (2023) https://doi.org/10.1117/12.2669331

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Application of fluorescent probes for cancer treatment Paper

Zixi Xiao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110X (2023) https://doi.org/10.1117/12.2669004

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Electrochemical biosensors based on microfluidic chips Paper

Chaoran Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110Y (2023) https://doi.org/10.1117/12.2669567

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Microfluidics integrated biosensors for healthcare monitoring Paper

Chenlong Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126110Z (2023) https://doi.org/10.1117/12.2669008

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Biomedical mechanism and application of genetically encoded fluorescent protein biosensors Paper

Huang Dun, Youdong Li, Nuo Zhou

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261110 (2023) https://doi.org/10.1117/12.2669335

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Silver nanoparticles for advanced electrochemical aptamer sensor Paper

Wanqi Zhao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261111 (2023) https://doi.org/10.1117/12.2669035

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Coronary intravascular imaging and physiological function for optimization of percutaneous coronary intervention Paper

Tonghanyu Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261112 (2023) https://doi.org/10.1117/12.2668957

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A review of the application of wireless positioning technology in micro robots in vivo Paper

Xinwei Huang, Maohao Li, Qingrun Shi, Junwei Zeng

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261113 (2023) https://doi.org/10.1117/12.2669949

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A review of tactile sensors used in surgical robots Paper

Yimiao Dong, Zixiao Huo

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261114 (2023) https://doi.org/10.1117/12.2669398

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The current status of finite element analysis in the application of total knee arthroplasty and corresponding method of improvement Paper

Zhengguang Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261115 (2023) https://doi.org/10.1117/12.2668993

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Applications of self-aggregating peptide as a novel bio-nanomaterial Paper

Xinyi Zhu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261116 (2023) https://doi.org/10.1117/12.2669015

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Peptides are widely found in natural organisms and play a variety of biological functions in human body. Compared with traditional materials, peptides have lower immunogenicity and better biocompatibility, which makes them ideal biological materials. Self-aggregating peptide is a kind of peptide chain that can be assembled by covalent binding of monomers under physiological or pathological conditions. Their advantages include the ability to aggregate by themselves and their low immunogenicity and biocompatibility as peptides. Therefore, self-aggregating peptides have various potential applications in biology and medical field. Since self-aggregating peptide can self-assemble into insoluble particles under certain conditions, wrapping the target protein with self-aggregating peptide can achieve the purpose of protein purification by simple centrifugation. This method is superior to the existing protein purification methods, since the experimental efficiency and cost can be optimized. Moreover, self-aggregating peptides, because of their peptide nature, do not elicit strong immune responses. Thus, self-aggregating peptides can be loaded with a large number of drugs and can be biodegraded into unharmful products which can be smoothly absorbed by the human bodies. The self-aggregated peptide loaded subunit vaccine can successfully induce and enhance immune response without adverse reactions, which is superior to existing immune adjuvants. Self-aggregated peptide also helps keeping the vaccine active for a long time and effectively reduce the cost of vaccine promotion. Select self-aggregating peptides that can be cleaved under pathological conditions to load drugs can help achieve drug targeting. In addition, the self-aggregating peptides loaded with drugs can be stored in specific sites for a long time, so that it does not require repeated dosing, thus improving the efficiency of drug administration. In this paper, the design of peptide self-assembly based solutions and their different biomedical applications are summarized, and their future prospects are prospected.

Review on current research and application of sEMG Paper

Tianyun Xu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261117 (2023) https://doi.org/10.1117/12.2669036

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An overview of bioinformatics technology application in the study of novel coronavirus Paper

Xin Tang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261118 (2023) https://doi.org/10.1117/12.2669630

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Encapsulated gold nanoparticle probes for virus detection Paper

Jinxuan Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261119 (2023) https://doi.org/10.1117/12.2669401

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Near-infrared brain imaging based on nanomaterials Paper

Yiqun Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111A (2023) https://doi.org/10.1117/12.2669410

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The implantable and wearable biosensors for blood sugar level detection Paper

Zichen Gao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111B (2023) https://doi.org/10.1117/12.2669033

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Molecular imaging in Alzheimer's disease Paper

Alina Dang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111C (2023) https://doi.org/10.1117/12.2669053

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Prediction of bio-active peptides in Coffea arabica with bioinformatics methods Paper

Junlin Tan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111D (2023) https://doi.org/10.1117/12.2669349

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Application of 3D printing technology and related materials in total hip arthroplasty Paper

Chaoyi Zhou

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111E (2023) https://doi.org/10.1117/12.2669952

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Enhancing multi-domain stability of nnU-Net based LGE-CMR left atrium segmentation using the correct data augmentation strategy Paper

Mian Jiang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111F (2023) https://doi.org/10.1117/12.2669561

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Advanced design of next-generation glucose biosensors Paper

Mingyang Xia

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111G (2023) https://doi.org/10.1117/12.2670402

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Medical Science

Underlying mechanisms of schizophrenia and bipolar disorder Paper

HeLu Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111H (2023) https://doi.org/10.1117/12.2668965

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HELLS: a novel prognostic marker for patients with different subtypes of cervical cancer Paper

Jiaqi Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111I (2023) https://doi.org/10.1117/12.2669969

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Progress of research on tumor microenvironment and immunotherapy Paper

Chuiyu Kong

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111J (2023) https://doi.org/10.1117/12.2668991

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The association between nutrition pattern and heart disease in an elderly population in China Paper

Xiang Li, Tong Meng, Zizheng Shen, Zhuoran Sun

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111K (2023) https://doi.org/10.1117/12.2670024

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Design of a novel CAR T system targeting glioblastoma Paper

Yifei Qiu, Lei Huang, Aojie Guo, Qiujie Wang, Liyuan Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111L (2023) https://doi.org/10.1117/12.2669343

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The benefit of directed forgetting can be improved by training Paper

Xingru Qiu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111M (2023) https://doi.org/10.1117/12.2669934

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Neuroinflammation as a core pathogenic mechanism of Alzheimer’s disease: recent research advances and related therapeutical approaches Paper

Zongzheng Xue

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111N (2023) https://doi.org/10.1117/12.2669000

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Multi-responsive polymer-coated hollow mesoporous silica nanoparticle-based drug delivery system for targeted cancer therapy Paper

Tingyu Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111O (2023) https://doi.org/10.1117/12.2669391

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Effective treatment of cancer has always been a medical field that is constantly being explored all over the world. Currently, the main means of cancer treatment are surgery, chemotherapy and radiotherapy. In recent years, the application of nanomaterials in the field of biomedicine has been highly anticipated. Nanomedicine is safer and more effective than traditional therapies, especially in distinguishing cancer cells from normal tissues. Nanomedicine plays an irreplaceable role in targeted drug controlled release system. Among them, silica nanoparticle-based and functionalized systems with highly controllable size and shape, low toxicity, good biocompatibility, stability in physiological conditions, and stimuli-responsive capping agents have promoted this research. A functional polymer with dual or triple response to silica nanocarriers provides a reliable solution for precise control of release and enhancement of cancer curative effect. This paper focuses on the experimental research of introducing multifunctional stimulus-responsive mesoporous silica nano-drug carriers, and provides some opinions on typical successful drug delivery, which are as follows. (1) Dual-pH sequential release of arsenic trioxide (ATO) and paclitaxel (PTX) was achieved using mesoporous silica nanoparticles coated with polyacrylic acid (PAA) and pH sensitive lipids (PSL); (2) Efficient encapsulation of DOX with HMSN, followed by β-cyclodextrin overlaid on the disulfide bond of glutathione, and finally the surface of the particles was decorated with amantanide-containing citrate functionalized polylysine (PLL(cit)-Ad) for pH/GSH-dual responsive controlled release through subject-object interaction; (3) Atom transfer radical polymerization which is initiated on surface developed based on PDEAEMA-modified hollow mesoporous silica nanoparticles (HMSN) as pH-, reduction-, and light-responsive nanocarriers. Finally, potential problems and development prospects of multifunctional MSNs for biocarrier are summarized.

The advantages of erythritol compared with the common natural sweeteners in the market and current uses in the food and food industries Paper

Yunjie Ruan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111P (2023) https://doi.org/10.1117/12.2669473

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Current options for the treatment of advanced or metastatic NSCLC Paper

Hsuan-Yi Lee

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111Q (2023) https://doi.org/10.1117/12.2669366

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Late-life depression and related interventions: a review Paper

Yuhan Shuai

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111R (2023) https://doi.org/10.1117/12.2669411

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Research on the 6XS6 of the SARS-CoV-2 spike protein Paper

Liyuan Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111S (2023) https://doi.org/10.1117/12.2669858

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Advances in treating HIV-1 infections Paper

Chang Xu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111T (2023) https://doi.org/10.1117/12.2669621

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Research progress of cognitive impairment in schizophrenia Paper

Yu Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111U (2023) https://doi.org/10.1117/12.2669620

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Depression: neurological disorder versus psychiatric disorder Paper

Chuhua Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111V (2023) https://doi.org/10.1117/12.2669636

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COVID-19 virus: the immune reaction to vaccines Paper

Zihe Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111W (2023) https://doi.org/10.1117/12.2669650

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Comprehensive study and review of coronary artery disease Paper

Changhao Luo, Yanji Tong

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111X (2023) https://doi.org/10.1117/12.2669657

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Mental stress and heart disease Paper

Xi Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111Y (2023) https://doi.org/10.1117/12.2669661

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The comparison between hippocampus and retrosplenial cortex in value-based decision-making Paper

Simin Huang, Yingda Li, Jiaqi Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126111Z (2023) https://doi.org/10.1117/12.2670176

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The mechanics involved in ADPKD and nephrolithiasis interaction Paper

Jerry X., Herbert W.

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261120 (2023) https://doi.org/10.1117/12.2669668

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Analysis of how different disease control and prevention strategies influence the spread of COVID-19 in a susceptible-infected-quarantined-recovered-died model Paper

Mian Wu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261121 (2023) https://doi.org/10.1117/12.2669533

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Research progress on prion protein structure and molecular mechanism of pathogenicity Paper

Yiran Zhao, Xiaoxiang Gong, Songying Jin, Lifan Luo

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261122 (2023) https://doi.org/10.1117/12.2669372

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The mechanism of HDAC6 affecting the progress of non-small cell lung cancer Paper

Yuchen Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261123 (2023) https://doi.org/10.1117/12.2669374

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The development of an electrochemical immunoassay to detect digoxin in whole blood via hybridization of DNA Paper

Ziyi Ning, Qiao Lin, Xueke Bai

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261124 (2023) https://doi.org/10.1117/12.2668994

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Diagnostic and neutralizing aptamers technology against Sars-Cov-2 Paper

Zhiling Guo

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261125 (2023) https://doi.org/10.1117/12.2669355

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High-risk regional distribution of gynecopathy in China in 2020 Paper

Zilun Cai, Zhiang Cui, Ruchen Duan, Yingxi Jin

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261126 (2023) https://doi.org/10.1117/12.2669001

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The correlation between mutated genes and leiomyosarcoma primary sites Paper

Kangqi Li, Shuyan Qiu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261127 (2023) https://doi.org/10.1117/12.2669579

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The functions of masks and vaccines: whether they can be interchange with each other Paper

Yefei Cui

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261128 (2023) https://doi.org/10.1117/12.2669342

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Effect of age and gender on alopecia in patients hospitalized with COVID-19 Paper

Qiang Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261129 (2023) https://doi.org/10.1117/12.2669937

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Research on the selection of therapy for Parkinson’s disease Paper

Jiazheng Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112A (2023) https://doi.org/10.1117/12.2669002

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Human papillomavirus infection and cervical cancer prevention in Indonesia Paper

Yanjia Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112B (2023) https://doi.org/10.1117/12.2670404

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The mechanism of sleep, dreams, and sleep deficiency Paper

Rena Qing

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112C (2023) https://doi.org/10.1117/12.2670178

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Sleep is a vital function to all species for reinvigorating the mental and physical senses. During sleep, specific synapses become less active to eliminate unneeded memories as other synapses strengthen to enhance memory consolidation. Healthy quality and longevity of sleep can also regulate moods by ridding fatigue and repairing integrity of the medial prefrontal cortex-amygdala connections. External disturbances affect the quality of sleep, and an individual's routine may play a role in the development of sleeping disorders. By irregulating the circadian rhythm and having consistent negative sleeping habits, sleep disorders such as insomnia, narcolepsy, and sleep apnea may develop. Eight to nine hours of sleep are recommended to both teenagers and adults, if less is received, difficulty in concentration and interpretation of information may be present, as well as physiological effects such as higher blood pressure caused by the disrupted regulation of stress hormones, which if continued, can make the body more prone to serious health conditions.The science of sleep and dreaming comprises a relevant thesis in modern neuroscience research and issues major comprehensions on the study of human consciousness. Dreams are an integral part of sleep. Sleep and dream cycles vary in phenomenology, characteristics, and under circumstances, interpretation of the individual. Various theories such as Sigmun Freud's Psychodynamic theory, the activation synthesis model, and the cognitive development theory have been created and numerous studies are ongoing as the principal motive of dreams has not yet been concluded. Some theories remain heavily physiological as high difficulty of investigations are discontinued by scientists and deemed unverifiable. The research presented here revolves around the neurology of sleep as to inquire into the physiology and investigations on the purpose of dreams. We thus conclude the current review with a call for further research directed towards the primary purpose of sleep and dream.

Analysis and prediction of monkeypox confirmed cases using ARIMA and LSTM: a comparative study Paper

Hanbei Xiong

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112D (2023) https://doi.org/10.1117/12.2669383

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The application and development of smart city technologies in public health during the COVID-19 pandemic Paper

Renrui Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112E (2023) https://doi.org/10.1117/12.2669062

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Research progress of targeted protein degradation Paper

Yixuan Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112F (2023) https://doi.org/10.1117/12.2669970

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Research on physiological signal analysis based on clinical statistics and machine learning Paper

Jiaqi Feng

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112G (2023) https://doi.org/10.1117/12.2669358

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The crosstalk between the “inflamed” mind and the “impulsive” mind: activation of microglia and impulse control disorders Paper

Yongqi Luo

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112H (2023) https://doi.org/10.1117/12.2669957

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The role of NRG1 in schizophrenia Paper

Jiaxuan Han, Jingnan Ru, Haoshen Zhai

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112I (2023) https://doi.org/10.1117/12.2669672

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The role of BDNF in bipolar disorder and related treatment Paper

Jiayi Li, Pengze Lin, Baoer Yuan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112J (2023) https://doi.org/10.1117/12.2669394

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A sequential-structural hybrid method for linear B-cell epitope prediction Paper

Baijiang Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112K (2023) https://doi.org/10.1117/12.2669539

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Treatment and efficacy of Kymriah for three types of blood cancers Paper

Zefeng Gao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112L (2023) https://doi.org/10.1117/12.2668990

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Treatment of diseases through stem cell bioengineering techniques Paper

Anyuxin Hu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112M (2023) https://doi.org/10.1117/12.2669485

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Risk prevention and early diagnosis of sports-related chronic brain injury Paper

Fei Lang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112N (2023) https://doi.org/10.1117/12.2669019

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Stereotactic body radiation therapy in brain metastases in the elderly population Paper

Shurui Lyu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112O (2023) https://doi.org/10.1117/12.2669486

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Introduction and analysis of fluorescence microscope improvement methods Paper

Yichi Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112P (2023) https://doi.org/10.1117/12.2669032

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Association between smoking status and oral health: NHANES 2013-2018 Paper

Yicheng Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112Q (2023) https://doi.org/10.1117/12.2669051

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The beneficial effect of the ketogenic diet on the treatment and management of type 2 diabetes Paper

Yiming Feng

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112R (2023) https://doi.org/10.1117/12.2669056

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Practice and exploration of telemedicine in the prevention and control of COVID-19 Paper

Shuyu Ye

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112S (2023) https://doi.org/10.1117/12.2669412

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A review of aberrant DNA methylation in bone marrow mesenchymal stromal cells: a new possible access of acute myeloid leukemia Paper

Xiao Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112T (2023) https://doi.org/10.1117/12.2669026

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The relationships between health-related risk behaviors and type 2 diabetes mellitus among US adult males Paper

Hong Cao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112U (2023) https://doi.org/10.1117/12.2669030

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The pathogenesis of Alzheimer's disease: the inflammation Paper

Zihang Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112V (2023) https://doi.org/10.1117/12.2669359

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The failure to establish herd immunity against SARS-CoV-2 Paper

Haohua Cui

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112W (2023) https://doi.org/10.1117/12.2669370

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Comparative study of machine learning algorithms for early autism spectrum disorder identification Paper

Mingzhong Tang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112X (2023) https://doi.org/10.1117/12.2669421

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ASD-associated gene: SHANK3 Paper

Jiuman Zhou

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112Y (2023) https://doi.org/10.1117/12.2669860

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The genes that contribute to bipolar disorder and its genetic therapy Paper

Chenjun Su

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112Z (2023) https://doi.org/10.1117/12.2669373

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Breast cancer screening strategy: what can we learn? Paper

Yue Zhang, Wenwei Zhang, Changzhi Zhou, Yitong Fang, Qiyi Yu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261130 (2023) https://doi.org/10.1117/12.2669403

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Analysis and reflection on the normalization of epidemic prevention and the construction of China's national public health system Paper

Zhixin Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261131 (2023) https://doi.org/10.1117/12.2669332

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Current development and limitations of chemotherapy and immunotherapy in triple-negative breast cancer Paper

Jingxi Lai

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261132 (2023) https://doi.org/10.1117/12.2669663

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Clinical problems associated with the spike protein D614G mutation in SARS-CoV-2 Paper

Shengxing Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261133 (2023) https://doi.org/10.1117/12.2669061

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Retrotransposons: the ‘dark matter’ benefiting the human genome Paper

Jiawei Fan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261134 (2023) https://doi.org/10.1117/12.2669380

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The effect of depressive symptoms on falls of middle-aged and elderly people based on the PSM method Paper

Ying Qiao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261135 (2023) https://doi.org/10.1117/12.2669341

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An overview of stem cell-based therapy towards the treatment of Alzheimer’s disease Paper

San-Chi Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261136 (2023) https://doi.org/10.1117/12.2669040

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Analysis of neural stimulation and crosstalk problems Paper

Wenhao Wu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261137 (2023) https://doi.org/10.1117/12.2669344

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Diagnosis, treatment, and prevention of tennis elbow Paper

Dingkun Chen, Zhiqi Lin, Yuxiang Liu, Huijia Zhou

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261138 (2023) https://doi.org/10.1117/12.2669337

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Diagnosis and management of acute hamstring strain injury Paper

Ziang Lin

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261139 (2023) https://doi.org/10.1117/12.2669334

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Impacts of muscle strength and flexibility on joints Paper

Sihan Huang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113A (2023) https://doi.org/10.1117/12.2669656

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Psychological prevention and treatment and rehabilitation for sports injuries Paper

Wentong Han

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113B (2023) https://doi.org/10.1117/12.2669961

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Symptom and treatment of lateral ankle sprain Paper

Xin Shen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113C (2023) https://doi.org/10.1117/12.2669653

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Effect of vitamin D on obesity and its role in the microbiota-gut-brain axis Paper

Zeyongsheng Jin, Yi Yin, Jing Zhu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113D (2023) https://doi.org/10.1117/12.2669654

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Regulation of low-fat diet on obesity and type 2 diabetes in adolescents Paper

Yiwen Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113E (2023) https://doi.org/10.1117/12.2669933

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The role of P53 in cancer and infectious disease Paper

Jiaxin Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113F (2023) https://doi.org/10.1117/12.2669658

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The possibility of MSLN, ANTXR1, and ROR1 to become the target of CAR T cell therapy for treating TNBC and lung cancer Paper

Jianshi Zhu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113G (2023) https://doi.org/10.1117/12.2669662

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The roles of BUB1/BUB1B/BUB3 in human breast cancer Paper

Chenyue Hou

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113H (2023) https://doi.org/10.1117/12.2669869

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How does exercise impact obesity in terms of its prevention or treatment? Paper

Linli Zhu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113I (2023) https://doi.org/10.1117/12.2669665

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Investigations on topologically associated domains from functional, evolutionary, and technical perspectives Paper

Baoqin Fei

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113J (2023) https://doi.org/10.1117/12.2669666

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Current treatment of autism spectrum disorder Paper

Jiayang Xu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113K (2023) https://doi.org/10.1117/12.2669675

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Why psychotherapy can treat depression Paper

Zhiyin Ding

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113L (2023) https://doi.org/10.1117/12.2669677

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The causes of major depressive disorder Paper

Bo Xu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113M (2023) https://doi.org/10.1117/12.2669489

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The research progress on related genes affecting depression and their roles in rodent models Paper

Chengze Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113N (2023) https://doi.org/10.1117/12.2669363

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The culture and application of patient-derived tumour organoids Paper

Xiaoyu Ren

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113O (2023) https://doi.org/10.1117/12.2669049

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Difficulties and advance of CAR-T therapy in hepatocellular carcinoma Paper

Siyu Zhu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113P (2023) https://doi.org/10.1117/12.2669678

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Research on the propagation model of COVID-19 based on virus dynamics Paper

Jiahao Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113Q (2023) https://doi.org/10.1117/12.2669681

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Exploring recent advances and limitations in CAR-T therapy for glioblastoma multiforme Paper

Sixing Luo

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113R (2023) https://doi.org/10.1117/12.2669007

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Antimicrobial resistance mechanisms: using examples from gram-positive and gram-negative bacteria Paper

Zhiwen Xiao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113S (2023) https://doi.org/10.1117/12.2669646

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The bottleneck of CAR-T cell therapy Paper

Yuyin Gui

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113T (2023) https://doi.org/10.1117/12.2669935

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Application of MSCs therapy in COVID-19 Paper

Yaowen Feng

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113U (2023) https://doi.org/10.1117/12.2669954

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Effects of inspiratory muscle training on athletic performance and its physiology in athletes with moderate-to-high intensity sports Paper

Fanqi Yi

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113V (2023) https://doi.org/10.1117/12.2669972

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The application of monoclonal antibody immunotherapy in cancer treatment Paper

Muran Song

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113W (2023) https://doi.org/10.1117/12.2669347

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Alcohol intake and depression in women aged ≥21 years: NHANES 2013–2016 Paper

Ziang Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113X (2023) https://doi.org/10.1117/12.2669975

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Using linear regression model to explore the relationship between testosterone and SUA in adult males: NHANES 2013–2016 Paper

Hongyi Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113Y (2023) https://doi.org/10.1117/12.2669014

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The transmissibility of Covid-19: a modelling study in China Paper

Baosheng Yin

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113Z (2023) https://doi.org/10.1117/12.2669564

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Lactate: the underestimated metabolite and its important roles in cell regulation Paper

Qinhui Huang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261140 (2023) https://doi.org/10.1117/12.2669945

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Breast Cancer Treatment: Adoptive Immunotherapy, Combination Therapy, and Future Perspectives Paper

Xinyue Jian, Shuwen Ge

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261141 (2023) https://doi.org/10.1117/12.2669027

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Immune checkpoint inhibitors for non-small cell lung cancer treatment Paper

Zining Guo, Zhixiang Wu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261142 (2023) https://doi.org/10.1117/12.2669948

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CAR-T cell toxicity: clinical manifestation, contributive factors, and recommendations Paper

Haozhu Liu, Jiajun Wu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261143 (2023) https://doi.org/10.1117/12.2669625

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Application of n-3 polyunsaturated fatty acids in the treatment of type 2 diabetes mellitus and its complications Paper

Tiannan Zhou

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261144 (2023) https://doi.org/10.1117/12.2670029

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A study of hypoxia-inducible factor (Hif)-2α, a specific prognostic marker for patients with lung adenocarcinoma Paper

Youkai Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261145 (2023) https://doi.org/10.1117/12.2669376

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Adolescent obesity and its main causes: analysis and review Paper

Yuzhe Ren

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261146 (2023) https://doi.org/10.1117/12.2669951

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Predictive diagnosis of diabetes based on multiple linear regression Paper

Boxing Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261147 (2023) https://doi.org/10.1117/12.2669013

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Current research progress on Alzheimer's disease treatment targeting tau protein Paper

Zhimo Jiang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261148 (2023) https://doi.org/10.1117/12.2668967

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Earlier diagnosis of Alzheimer’s disease by identifying risk factors and utilizing biomarkers Paper

Jianzhou Xu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261149 (2023) https://doi.org/10.1117/12.2669022

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Apolipoprotein A-1 in the treatment of acute myocardial infarction Paper

Haowen Xue

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114A (2023) https://doi.org/10.1117/12.2669857

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Prevention and treatment of the taeniasis and cysticercosis Paper

Yuchen Cao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114B (2023) https://doi.org/10.1117/12.2669638

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The structure of lentinan and its effects on immunomodulation, antitumour, and antiviral Paper

Xiaorong Jin

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114C (2023) https://doi.org/10.1117/12.2669637

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Diagnosis and non-operative treatment of medial collateral ligament Paper

Tong Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114D (2023) https://doi.org/10.1117/12.2669028

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Diagnosis and non-operative treatment of lumbar disc herniation Paper

Dongchen Li, Jiacheng Yang, Shuo Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114E (2023) https://doi.org/10.1117/12.2669956

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Glucagon-like peptide 1 receptor agonists in the treatment of type II diabetes Paper

Xi Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114F (2023) https://doi.org/10.1117/12.2669050

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Prevalence and prevention of HBV: the necessity of functional cure Paper

Ziang Xu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114G (2023) https://doi.org/10.1117/12.2668987

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sFlt-1: a potential new therapeutic protein to treat rheumatoid arthritis Paper

Ruizi Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114H (2023) https://doi.org/10.1117/12.2668961

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Due to the inability of immune system to identify certain proteins as self-antigens, rheumatoid arthritis (RA), a chronic, inflammatory, and autoimmune disorder that predominantly affects the joints, causes inflammation in the afflicted body parts. Both hereditary and environmental variables converge to cause RA. Anti-angiogenesis likely serves as a treatment approach as it is crucial to the maintenance of synovitis in RA. sFlt-1 is an angiogenic factor which functions by interacting with VEGF cytokines to compete with VEGF receptor to bind VEGF in order to obstruct cell signaling and hence halt angiogenesis. The absence of the transmembrane and cytoplasmic domains of sFlt-1, an alternatively spliced version of the VEGF receptor-1, ensures that binding will not cause inflammation. Decreased production of new blood vessels results in less joint inflammation and pannus development. That is what the therapy aims to treat so sFlt-1 is appropriate for use in anti-angiogenic therapy. In addition to the pathogenesis of the RA and the workings mechanism of sFlt-1, this article also mentions the detailed manufacturing process of sFlt-1: vector selected with specific HaloTag® tag, transformation by heat shock, transfection in A549 cells, extraction from culture and purification through HaloTag® protein purification and SEC method. Although the entire production process seems seamless, it can become very challenging in practice. Although challenging, the circumstances in which the biological reagents are maintained and cultured cells must be tightly managed. Besides, other social, ethical and economic concerns should also be taken into account. The system used specifically is the vesicular drug delivery system. Additionally, difficult therapeutic testing of sFLit-1is inevitable. sFlt-1 is still of significant research interest and has the potential to develop into a novel commercial treatment, even though there is not enough experimental evidence to demonstrate how successful it is in treating RA as a disease.

A real-world data-based safety profiling of monoclonal antibodies Paper

Shihang Zeng

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114I (2023) https://doi.org/10.1117/12.2668963

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The causes of schizophrenia in adolescents Paper

Qixian Gao, Yunwen Ma, Zefeng Yuan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114J (2023) https://doi.org/10.1117/12.2669381

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sRAGE: potential therapeutic target for Alzheimer’s disease Paper

S. Danning Zhu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114K (2023) https://doi.org/10.1117/12.2669633

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Effects of sugar substitutes on health concerns and corresponding mechanisms related to gut microbiota Paper

Xin Fang, Letao Wang, Yilin Ying

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114L (2023) https://doi.org/10.1117/12.2669563

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A comprehensive study on the efficacy of fecal microbiota transplantation in irritable bowel syndrome Paper

Yunda Dai, Zuheng Qin

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114M (2023) https://doi.org/10.1117/12.2669632

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Effects of Mediterranean dietary patterns on the treatment of type 2 diabetes mellitus Paper

Xinyi Chen, Yeqi Deng

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114N (2023) https://doi.org/10.1117/12.2669017

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Advance on the influence mechanism of intestinal flora on osteoporosis Paper

Shuyun Xue

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114O (2023) https://doi.org/10.1117/12.2669039

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Clinical efficacy and safety of ketogenic diet Paper

Ziang Li, Jiaye Liu, Kaixin Liu, Xinyi Tang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114P (2023) https://doi.org/10.1117/12.2669631

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Depression in menopausal women Paper

Wanting Shan, Hanrui Dou, Yundi Gui

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114Q (2023) https://doi.org/10.1117/12.2669562

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Near-infrared light-induced PDT/PTT synergistic phototherapy of cancer Paper

Wenqian Liu, Yucong Wen, Jiajun Yu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114R (2023) https://doi.org/10.1117/12.2669404

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Role of 5-HT receptors and transporters in psychiatric disorders Paper

Jiayi Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114S (2023) https://doi.org/10.1117/12.2668997

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Prediction of polycystic ovary syndrome with statistical models Paper

Qianhui Ma

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114T (2023) https://doi.org/10.1117/12.2668992

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Predicting mortality in patients with heart failure based on machine learning approaches Paper

Xuan Du, Tianhui Huang, Shini Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114U (2023) https://doi.org/10.1117/12.2669045

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Risk assessment for heart failure using multiple linear regression model Paper

Yifan Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114V (2023) https://doi.org/10.1117/12.2668989

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Ketogenic diet for obesity: benefits and potential improvement Paper

Yiwen Xu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114W (2023) https://doi.org/10.1117/12.2669357

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An overview of the development of past and current drug treatments for obesity in the United States Paper

Yuan Liang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114X (2023) https://doi.org/10.1117/12.2669531

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Risk factor and regression analysis for diabetes Paper

Wandi Su, Yi Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114Y (2023) https://doi.org/10.1117/12.2669384

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Attribution and regression analysis based on data of COVID-19 and character strengths Paper

Xingni Wan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114Z (2023) https://doi.org/10.1117/12.2669628

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Analysis of risk factor for Alzheimer's disease based on the data of ADNI Paper

Yilun Jiang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261150 (2023) https://doi.org/10.1117/12.2669424

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Study on the regularity of traditional Chinese medicine dietary prescription for type 2 diabetes mellitus based on cluster analysis Paper

Yuhan Gao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261151 (2023) https://doi.org/10.1117/12.2668998

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PROTACS: an emerging strategy for intracellular and integral membrane protein degradation Paper

Yifan Huang, Hanxie Shen, Yu Sun

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261152 (2023) https://doi.org/10.1117/12.2669371

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CRISPR-Cas9 system applications in cancer models Paper

Qiancheng Jiang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261153 (2023) https://doi.org/10.1117/12.2669382

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The quantitative genetic study on the Alzheimer’s disease Paper

Chuanjia Ju

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261154 (2023) https://doi.org/10.1117/12.2669388

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Effects of type-2 diabetes on the corticosteroid therapy for COVID-19 pneumonia Paper

Yang Wang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261155 (2023) https://doi.org/10.1117/12.2669396

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Mutations of MYH7 gene and potential therapeutic target for HCM Paper

Yi Wu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261156 (2023) https://doi.org/10.1117/12.2669387

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Study of meniscus injuries and treatment in football players Paper

Songyu Xing

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261157 (2023) https://doi.org/10.1117/12.2669423

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Regression analysis for potential indicators of diabetes Paper

Yiqi Zhou

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261158 (2023) https://doi.org/10.1117/12.2669392

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Prolongation of tetrodotoxin’s anesthetic effect Paper

Linghang Qu, Sian Xue, Qiwen Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261159 (2023) https://doi.org/10.1117/12.2668984

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Research progress on familial medullary thyroid cancer Paper

Yuxin Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115A (2023) https://doi.org/10.1117/12.2669400

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Stroke in China: disease burden and attributable risk factors Paper

Wenxin Tian

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115B (2023) https://doi.org/10.1117/12.2669414

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Effects of vitamin D intake by diet and supplements on cardiovascular health among pregnant US women Paper

Man Jiang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115C (2023) https://doi.org/10.1117/12.2669547

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Risk and demographic factors examination models for lung cancer incidences in the United States Paper

Jiayu Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115D (2023) https://doi.org/10.1117/12.2669548

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The global burden of depressive disorder from 1990 to 2019: a systematic analysis for the global burden of disease study 2019 Paper

Xinyu Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115E (2023) https://doi.org/10.1117/12.2669550

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Use of logistic regression, nonlinear regression, and linear regression in lung cancer research Paper

Zhuonan Yu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115F (2023) https://doi.org/10.1117/12.2669953

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Effect of drug injection and stimulated learning on trisomic mice expressions of APP and SOD1 Paper

Shizhe Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115G (2023) https://doi.org/10.1117/12.2669963

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Explore the relationship and differences in death and vaccination in the US and UK Paper

Xinyi Deng

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115H (2023) https://doi.org/10.1117/12.2669968

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Associations between body factors and heart disease using logistic regression and machine learning Paper

Shu Pang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115I (2023) https://doi.org/10.1117/12.2669971

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Potential relation between Covid-19 vaccines and Covid-19 death number Paper

Wenyu Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115J (2023) https://doi.org/10.1117/12.2669950

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Reasonable proportion of nutrition intake and life expectancy Paper

Shiya Sun

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115K (2023) https://doi.org/10.1117/12.2669955

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Mental health and the factors with people in tech workspace Paper

Shiyu Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115L (2023) https://doi.org/10.1117/12.2669959

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Population-based spatial level analysis on Alzheimer’s disease mortality and potential risk factors Paper

Liheng Yang, Xiaowei Huang, Qirui Zhao, Limeng Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115M (2023) https://doi.org/10.1117/12.2669559

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Exploring the key factors related to the risk of heart disease by applying classification methods Paper

Junyi You

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115N (2023) https://doi.org/10.1117/12.2669962

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Convolutional Siamese network-based few-shot learning for monkeypox detection under data scarcity Paper

Runze Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115O (2023) https://doi.org/10.1117/12.2669964

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Predictive model analysis of stroke disease based on machine learning Paper

Xiangchu Sun

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115P (2023) https://doi.org/10.1117/12.2669554

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Insisting with mask or demanding for more: plights of the transmission of airborne diseases Paper

Youji Zhu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115Q (2023) https://doi.org/10.1117/12.2668904

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Pharmaceutical Science

Advances in carbapenem resistance and hypervirulence of Klebsiella pneumoniae Paper

Yuchang Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115R (2023) https://doi.org/10.1117/12.2669528

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Comparison and improvement of different approaches of morphine synthesis Paper

Ziye Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115S (2023) https://doi.org/10.1117/12.2669557

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Tumor microenvironment factors effects on TMZ-resistance and TMZ-resistance acquiring in glioblastoma cells Paper

Caihao Nie

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115T (2023) https://doi.org/10.1117/12.2669640

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Recent research progress on the role of BCL2 in cancer and related drugs Paper

Yubo Jianga, Yanbin Luan, Shuyan Wang, Baoyue Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115U (2023) https://doi.org/10.1117/12.2669368

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The mechanism and prospects of HPV vaccine Paper

Xuanyu Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115V (2023) https://doi.org/10.1117/12.2669023

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Therapeutic cancer vaccines in advanced melanoma: mechanism, application, and future direction Paper

Jiaying Hao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115W (2023) https://doi.org/10.1117/12.2669534

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Recent update of PD-L1 inhibitor therapy and companion diagnostics Paper

Bicheng Jiang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115X (2023) https://doi.org/10.1117/12.2669047

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Using T-cell surface glycoprotein CD4 as an example to explore the impact of protein structure predicted by AlphaFold2 for structure-based drug discovery Paper

Yinjie Zhong

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115Y (2023) https://doi.org/10.1117/12.2669006

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A novel design of COVID-19 vaccine with high effectiveness and popularization Paper

Jielin Meng, Haotian Sun, Ruoyu Zhu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126115Z (2023) https://doi.org/10.1117/12.2669364

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Current situation and perspective of COVID-19 mRNA vaccine Paper

Qi Teng, Ziqi Wang, Yuhan Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261160 (2023) https://doi.org/10.1117/12.2669065

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Antiviral drugs against influenza viruses: oseltamivir and baloxavir Paper

Shiyun Liang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261161 (2023) https://doi.org/10.1117/12.2669580

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Design principle and development of vaccine in COVID-19 Paper

Hecong Qin

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261162 (2023) https://doi.org/10.1117/12.2669535

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Propranolol and nifedipine efficacy against hypertension Paper

Juntao Shi

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261163 (2023) https://doi.org/10.1117/12.2669574

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The treatment of Rukobia in AIDS: from lead compound to clinical trial Paper

Chixiang Ma, Yuxin Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261164 (2023) https://doi.org/10.1117/12.2669541

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Every year, few novel drugs were approved by FDA, getting the chance to go public. Their treatment on different diseases interested the authors to find the reason why a certain drug can apply on the treatment from the initial state to the finished medicines and the efforts scientists took for the therapy of diseases. The Rukobia is a good option approved by FDA in 2020 as a novel HIV-1 treatment drug which can help the treatment for multi-drug resistance patients. With the rapidly increasing HIV patients, developing countries need to control and cure the patients with HIV and the treatment for those multi-drug resistance patients can effectively prolong their lives. Present drug therapy can’t satisfy the necessary of AIDS patients and the usual treatment cocktail therapy bring patients high drug resistance of first line drugs which means the patients will have no excellent alternative treatment after the cocktail therapy, finishing their lives with no hope. Although the HIV can be treated by the specific gene treatment but it can’t be applied on most of patients and the completely curative patients are only 4 until now, as a result, the drug treatment is still important for HIV therapy. Rukobia can’t cure the AIDS because the high replication rate of the HIV can’t be completely killed in the short time so the drug resistance will also produce after a period of treatment but the novel active site make it different from the known antiviral drugs. The authors want to explore the mechanism of Rukobia and the relationship between the drug development and treatment so Rukobia is a good option which applied the new standard and new methods so it has strong reference meaning for this review. In the future, scientists including the authors can apply the mentioned researching method the development and treatment of the new drugs for other diseases and the Rukobia treatment is summarized more clearly in this review.

The discovery and development of Rukobia Paper

Shiqi Chen, Mengshan Yan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261165 (2023) https://doi.org/10.1117/12.2669009

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The importance of the clinical trialing process in the development of modern-day drugs Paper

Alan Ying

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261166 (2023) https://doi.org/10.1117/12.2669042

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Therapeutic strategies for Alzheimer's: treatment with traditional Chinese medicine Paper

GengCheng Liu, Wenqing Zhang, Mingyi Zhan, YiCheng Zhu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261167 (2023) https://doi.org/10.1117/12.2669020

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Clinical use of immune checkpoint inhibitors in cancer treatment: significance and limitations Paper

Yi Liu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261168 (2023) https://doi.org/10.1117/12.2669660

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Progress and perspectives of antibody-drug conjugates in cancer treatment Paper

Minglu Xu

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261169 (2023) https://doi.org/10.1117/12.2669936

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mRNA vaccines in cancer immunotherapy: clinical benefits, limitations, and future Paper

Sijia Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116A (2023) https://doi.org/10.1117/12.2669938

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Potential application of mesenchymal stem cells exosomes for drug loading Paper

Xiangyu Gao

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116B (2023) https://doi.org/10.1117/12.2669976

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The role of quercetin and curcumin in the treatment of COVID-19 infection: potential for combination of natural compounds Paper

Yueqi Zhang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116C (2023) https://doi.org/10.1117/12.2669977

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Using nanoparticles and nano-drugs in the treatment of pancreatic cancer Paper

Xizhe Kuang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116D (2023) https://doi.org/10.1117/12.2669634

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Brief summary of cisplatin nephrotoxicity Paper

KingWun Lau

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116E (2023) https://doi.org/10.1117/12.2669859

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Efficacy and limitations of pembrolizumab for lung cancer and Hodgkin lymphoma Paper

Zhiqian Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116F (2023) https://doi.org/10.1117/12.2669397

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Treating oral cancer with targeted therapy drugs: from beginning to bench-side Paper

Yao Huang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116G (2023) https://doi.org/10.1117/12.2670386

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Clinical research progress of lorlatinib in progressive non-small cell lung cancer Paper

Xuanlin Qi

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116H (2023) https://doi.org/10.1117/12.2669018

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Synthesis and efficacy analysis of multi-target TKI drug nintedanib Paper

Yuxin Li

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116I (2023) https://doi.org/10.1117/12.2669351

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Three classic synthetic paths of fostamatinib and its applications Paper

Yi Shan

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116J (2023) https://doi.org/10.1117/12.2669629

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An analysis of existing literature and data on adverse reactions with different characteristics of influenza vaccines and their safety credentials Paper

Yongxi Chen

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116K (2023) https://doi.org/10.1117/12.2668970

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Analysis on the research progress and prospect of novel coronavirus vaccine Paper

Nan Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116L (2023) https://doi.org/10.1117/12.2669352

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Application of reverse docking in traditional Chinese medicine research Paper

Yeye Ji

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116M (2023) https://doi.org/10.1117/12.2669488

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Erratum: Volume 12611

Electrochemical biosensors based on microfluidic chips (Erratum) Open Access

Chaoran Yang

Proceedings Volume Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126116Q (2023) https://doi.org/10.1117/12.2691007

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